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Panxeon blood test detects early-stage pancreatic cancer with 87% accuracy
An international research team, led by City of Hope, has developed a new liquid biopsy blood test called Panxeon that can detect pancreatic cancer in its early stages with high accuracy. Published in Nature Medicine, the study involved approximately 1,800 participants across the US, Europe, and Asia.
The Panxeon test utilizes an artificial intelligence algorithm to analyze three specific biomarkers: circulating microRNA, exosomal microRNA, and the CA 19-9 protein. In clinical testing, the method successfully identified pancreatic cancer in stages 1 and 2 in approximately 87% of cases. It also demonstrated a low false-positive rate of 3% among low-risk individuals.
Beyond cancer detection, the test showed significant promise in identifying high-grade dysplasia—a precancerous condition—in over 64% of patients with high-risk pancreatic cysts. This innovation could potentially transform the management of pancreatic adenocarcinoma, a disease that is often diagnosed too late for effective treatment, as current five-year survival rates remain low.
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- [● 5 SOURCES] The test identified high-grade dysplasia in over 64% of patients with high-risk pancreatic cysts. www.cnnbrasil.com.br · brasil.perfil.com · www.doctissimo.fr · cretaone.gr · www.evimaserres.gr
- [● 5 SOURCES] The Panxeon test combines microRNA, exosomal microRNA, and the CA 19-9 protein. www.cnnbrasil.com.br · www.doctissimo.fr · cretaone.gr · www.evimaserres.gr · brasil.perfil.com
- [● 5 SOURCES] The test resulted in a false-positive rate of 3% among low-risk individuals. www.cnnbrasil.com.br · www.doctissimo.fr · cretaone.gr · www.evimaserres.gr · brasil.perfil.com
- [● 5 SOURCES] The test utilizes an artificial intelligence algorithm to process molecular markers and calculate a risk score. brasil.perfil.com · www.doctissimo.fr · cretaone.gr · www.evimaserres.gr · www.cnnbrasil.com.br
- [● 5 SOURCES] The study results were published in the journal Nature Medicine. www.cnnbrasil.com.br · brasil.perfil.com · www.doctissimo.fr · cretaone.gr · www.evimaserres.gr
- [● 5 SOURCES] The international study involved approximately 1,800 participants from the US, Europe, and Asia. www.cnnbrasil.com.br · brasil.perfil.com · www.doctissimo.fr · cretaone.gr · www.evimaserres.gr
- [● 5 SOURCES] The Panxeon test detected pancreatic cancer in stages 1 and 2 in approximately 87% of cases. www.cnnbrasil.com.br · brasil.perfil.com · www.doctissimo.fr · cretaone.gr · www.evimaserres.gr
- [● 3 SOURCES] The research was led by City of Hope. cretaone.gr · www.evimaserres.gr · www.doctissimo.fr