Researchers develop Zurich Blue nano-dye for medical imaging

A collaborative research team in Switzerland has developed a new ultra-bright nano-near-infrared dye called “Zurich Blue” to improve medical imaging. The material is designed to provide high-resolution images of brain structures, aiding in disease detection and the monitoring of medical treatments.

The dye is inspired by “Egyptian Blue,” a copper-containing pigment used in ancient Egypt over 4,500 years ago. While the original pigment is visible to the naked eye, it also fluoresces under near-infrared light. Researchers used flame synthesis and laser irradiation to create two-dimensional nanolayers that retain this brightness.

The project involved the “Nanomaterials in Health” laboratory at Empa in St. Gallen, ETH Zurich, Balgrist University Hospital, and the University of Zurich. While laboratory experiments have shown promising results, the team aims to further advance the material for clinical applications, including potential use in combining diagnostics with therapeutic agents.