Researchers investigate new treatments for infants exposed to opioids

Researchers are investigating new treatments to mitigate the long-term effects of opioid exposure in infants. The study involves a collaborative effort between scientists, animal models, and individuals with lived experience of drug use to find ways to improve the lives of babies exposed to methadone and other opioids in the womb.

Historically, newborn withdrawal was often unrecognized, leading to fatal outcomes. While the use of methadone as a synthetic opioid substitute has improved survival rates since the 1990s, gaps remain regarding the long-lasting developmental impacts of exposure. These effects can include difficulties with impulse control, anxiety, learning, and attention.

One area of current investigation involves determining if a gut supplement could provide benefits to these infants. The research team includes Professor Ju Lee Oei, a senior neonatologist at The Royal Hospital for Women in Sydney and the Mater Research Institute in Brisbane, alongside Associate Professor Kelly Clemens and Dr. Isobel Williams.