San Francisco 49ers defeat Miami Dolphins 35-13

The San Francisco 49ers defeated the Miami Dolphins 35-13 in Santa Clara, marking their second consecutive win by at least 20 points to start the season. The 49ers' offense was highly efficient, scoring touchdowns on each of their first five drives.

Running back Christian McCaffrey reached a major milestone by scoring his 100th career touchdown, becoming the fourth-fastest player in the Super Bowl era to reach the mark in 114 games. He also became only the third player to record at least 50 touchdowns with two different franchises.

Quarterback Brock Purdy delivered a near-perfect performance, completing 20 of 22 passes for 287 yards, including two passing touchdowns and one rushing touchdown. The Dolphins, led by quarterback Malik Willis, struggled against the 49ers' defense, suffering four sacks before scoring a late 77-yard touchdown pass to Ryan Miller.