San Francisco 49ers evaluate running backs amid Christian McCaffrey's injury concerns

The San Francisco 49ers held workouts for three running backs—Raheem Blackshear, Khalil Herbert and Owen Wright—to provide depth after running back Jordan James suffered a broken rib and Christian McCaffrey continues to battle recurring injuries. McCaffrey missed most of the 2024 season with Achilles tendinitis and a knee issue, but returned in 2025 to earn the NFL Comeback Player of the Year award, recording 1,202 rushing yards and ten touchdowns.

Betting markets are already projecting the 2026 NFL Comeback Player of the Year award, with quarterback Patrick Mahomes listed as the favorite at +185 odds, while defensive star Micah Parsons and others are also on the board. The odds reflect ongoing speculation about players recovering from major injuries and returning to prominence.