started · updated
Sapienza University study links high-fat diets to early brain metabolism changes
A study coordinated by Eugenio Barone at Sapienza University of Rome, published in the journal Redox Biology, reveals that high-fat diets can negatively impact brain metabolism and memory before the onset of obesity or diabetes.
The research identifies a very early window of vulnerability to metabolic stress. Findings indicate that alterations in brain metabolism occur prior to the development of systemic metabolic changes and cerebral insulin resistance.
Researchers identified a reduction in the protein Biliverdin Reductase A (BVRA) as a key factor in these early alterations. This protein is essential for regulating insulin response and cellular metabolism, helping brain cells adapt to metabolic stress. Additionally, the study suggests that these effects may be more pronounced in women.
Entities
Eugenio Barone · Redox Biology · Sapienza University of Rome
Claims
What the coverage asserts, and how many sources carry each claim.
- [● 3 SOURCES] The study was coordinated by Eugenio Barone from Sapienza University of Rome. www.dire.it · lecodellitorale.it · www.adnkronos.com
- [● 3 SOURCES] The research findings were published in the journal Redox Biology. www.dire.it · lecodellitorale.it · www.adnkronos.com
- [● 2 SOURCES] High-fat diets impact the brain more significantly in women. lecodellitorale.it · www.adnkronos.com
- [● 3 SOURCES] A reduction in Biliverdin Reductase A (BVRA) protein levels is a primary factor in these early metabolic alterations. www.dire.it · lecodellitorale.it · www.adnkronos.com
- [● 3 SOURCES] A high-fat diet affects brain metabolism and memory within a few weeks, prior to the development of obesity and diabetes. www.dire.it · lecodellitorale.it · www.adnkronos.com
- [● 3 SOURCES] Changes in brain metabolism occur before the onset of cerebral insulin resistance. www.dire.it · lecodellitorale.it · www.adnkronos.com