St. Louis Cardinals host Cincinnati Reds in June 2026 MLB series

The St. Louis Cardinals opened a three‑game series against the Cincinnati Reds at Busch Stadium on June 5‑6, 2026. The series debut was scheduled for Friday, June 5, at 8:15 p.m. ET, with Kyle Leahy (5‑3, 4.25 ERA) starting for the Cardinals, who were 32‑28 and third in the NL Central. The Reds were slated to start Brady Singer (2‑5, 6.18 ERA), with the club at 31‑30 and fifth in the division.

Both clubs entered the matchup with several players on the injured list, including the Cardinals' Nathan Church and Ramón Urías, and the Reds' Jose Treviño, Elly De La Cruz, and Ke’Bryan Hayes. Key hitters highlighted for St. Louis were Jordan Walker (.291/.355/.537, 15 HR, 44 RBI) and Alec Burleson (.287/.352/.443, 7 HR, 42 RBI). Cincinnati’s offensive leaders featured Elly De La Cruz (12 HR, 37 RBI) and Sal Stewart (12 HR, 36 RBI). The game was also covered by betting odds, with the Cardinals favored at -145 on the moneyline.