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Part of situation: Stanford research on dual human brain systems (3 clusters)

Stanford researchers find human brain may consist of two fused neural systems

neuroscience evolutionary biology brain development stem cell research Stanford Medicine

Researchers at Stanford University have discovered that the human brain may not be a single unified organ, but rather the result of two distinct neural systems that fused together through evolution over 500 million years ago.

Previously, it was believed that the entire brain developed from a single population of progenitor cells. However, new findings show that the forebrain and midbrain develop from a cell lineage expressing the Otx2 gene, while the hindbrain originates from a separate lineage expressing the Gbx2 gene. This biological distinction is also reflected in the structure of chromatin within the cells.

This evolutionary insight explains why certain neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA), selectively affect specific brain regions. By identifying these distinct developmental paths, scientists have successfully cultivated hindbrain motor neurons in a laboratory for the first time, potentially opening new avenues for treating these conditions.

Entities

Kyle Loh · Nature Neuroscience · Rayyan Jokhai · Stanford Medicine · Stanford University

Claims

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Sources

Reflections on New Hypotheses of a Dual Brain Structure – CEH [crev.info]
Não bộ con người có hai bước chuyển lớn ở tuổi 24 và 60 [baoquocte.vn]
Các nhà khoa học cho rằng não người có thể là hai cơ quan riêng biệt rồi hợp nhất từ hơn 500 triệu năm trước [genk.vn]
Nuestro cerebro podría ser en realidad dos órganos distintos unidos por la evolución [www.elnacional.cat]
Các nhà khoa học cho rằng não người có thể là hai cơ quan riêng biệt rồi hợp nhất từ hơn 500 triệu năm trước [kenh14.vn]
Cérebro humano pode ser dois órgãos distintos fundidos em um [www.leak.pt]
Het menselijk brein bestaat eigenlijk uit twee verschillende organen, zo blijkt uit onderzoek [newsmonkey.be]
New study finds the human brain may be 'two existing neural systems' packed into one skull [www.thecooldown.com]