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[HEALTH] · United States · 2 sources

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Statins linked to lower glaucoma risk and reduced need for eye surgery

A large-scale analysis of medical records suggests that statins, commonly prescribed to lower cholesterol, may be linked to a reduced risk of developing glaucoma and a slower progression of the disease.

Published in the British Journal of Ophthalmology, the study utilized a global database to compare over 420,000 individuals. Researchers found that statin users had a 15% lower risk of being diagnosed with open-angle glaucoma compared to a control group.

For those already diagnosed with glaucoma, statin use was associated with a significantly lower need for various interventions. Specifically, users showed a 36% lower risk of requiring incisional glaucoma surgery, a 55% reduced risk of minimally invasive glaucoma surgery (MIGS), and a 60% lower risk of undergoing selective laser trabeculoplasty (SLT).

While the findings are promising regarding the potential nerve-protecting effects of statins, researchers noted that medical record analyses cannot prove causation. Randomized controlled trials are required to confirm whether statins directly protect the optic nerve.

Entities

British Journal of Ophthalmology · University of California San Diego · University of South Florida · University of Southern California