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Tim Andrews survives 271 days with genetically modified pig kidney
A patient in the United States has set a new record for xenotransplantation, living for 271 days with a genetically modified pig kidney. Tim Andrews, a 66-year-old man from New Hampshire suffering from end-stage renal disease due to type 2 diabetes, used the animal organ as a 'bridge' to avoid dialysis while waiting for a human transplant.
The kidney, nicknamed 'Wilma', was sourced from a Yucatan miniature pig that underwent 69 genome edits. These modifications were designed to reduce the risk of immune rejection and prevent the transmission of animal viruses. The medical team at Mass General Brigham reported that the organ functioned effectively for nearly nine months before it eventually failed.
Following the failure of the porcine kidney, Andrews successfully received a human kidney from a deceased donor. This case is being highlighted by researchers as a significant milestone in addressing the global organ shortage, as the patient's chances of receiving a human kidney within five years were estimated at only 9% prior to the experimental procedure.
Entities
Mass General Brigham · New Hampshire · The Lancet · Tim Andrews · Wilma
Claims
What the coverage asserts, and how many sources carry each claim.
- [● 3 SOURCES] The pig kidney, named Wilma, was sourced from a genetically modified Yucatan miniature pig. cafebiz.vn · es.gizmodo.com · soha.vn
- [● 5 SOURCES] A genetically modified pig kidney functioned in a human patient for 271 days, setting a new record. bavaronews.com · www.tecnoandroid.it · cafebiz.vn · es.gizmodo.com · soha.vn
- [● 4 SOURCES] The xenotransplant allowed the patient to avoid dialysis for 271 days. bavaronews.com · cafebiz.vn · es.gizmodo.com · soha.vn
- [● 2 SOURCES] The risk of death or leaving the transplant waiting list was over 40% for the patient. cafebiz.vn · es.gizmodo.com
- [● 2 SOURCES] The pig kidney underwent 69 genome edits to improve compatibility and reduce viral risks. cafebiz.vn · soha.vn
- [● 3 SOURCES] The pig kidney was eventually replaced by a human kidney from a deceased donor. www.tecnoandroid.it · cafebiz.vn · soha.vn
- [● 2 SOURCES] The patient had a 9% chance of receiving a human kidney within five years prior to the procedure. cafebiz.vn · es.gizmodo.com
- [● 3 SOURCES] The patient, Tim Andrews, is a 66-year-old man from New Hampshire with end-stage renal disease caused by type 2 diabetes. cafebiz.vn · es.gizmodo.com · soha.vn