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[HEALTH] · United States · 6 sources

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UCSF researchers link ultra-processed food reduction to improved depression symptoms

Scientists at the University of California, San Francisco (UCSF) have reported a potential link between ultra-processed food consumption and depression. In a preliminary study published in JAMA Psychiatry, twenty patients reported moderate to significant improvements in three depression measures after reducing their intake of ultra-processed foods by more than 85 percent.

Researchers noted that the study is likely the first to compare depressive symptoms before and after a dietary shift from ultra-processed foods to healthier options. Dr. Andrew Krystal and researcher Nyasha Chagwedera highlighted the importance of the gut-brain connection, suggesting that ultra-processed foods may harm the gut in ways that impact brain function and dopamine release.

The research team emphasized that further studies are required to determine how specific factors, such as changes in macronutrient ratios (sugar and fats), calorie intake, and exposure to additives, preservatives, and stabilizers, influence mental health outcomes.

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American Medical Association · Andrew Krystal · JAMA Psychiatry · Nyasha Chagwedera · University of California, San Francisco

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