University of Colorado researchers study GAE as knee replacement alternative

Researchers at the University of Colorado are studying a minimally invasive procedure called genicular artery embolization (GAE) that may serve as an alternative to knee replacement surgery for patients with osteoarthritis.

GAE works by using a catheter to reach the blood vessels supplying the affected joint, selectively blocking abnormal vessels associated with inflammation. By reducing blood flow to these inflamed areas, the procedure aims to decrease swelling and chronic pain. While the treatment does not repair destroyed cartilage or cure osteoarthritis, it may improve mobility and provide relief for those who have not responded to conservative treatments like physical therapy or steroid injections.

Clinical studies, including a randomized controlled trial published in European Radiology, have tracked results over 12 months, showing reductions in pain and improved knee function. Medical professionals suggest the procedure is most promising for patients with mild to moderate osteoarthritis who are not yet ready for major surgery.