University of Dundee researchers discover new single-dose antimalarial compound

cabamiquine malaria treatment University of Dundee antimalarial compound single-dose therapy

Researchers at the University of Dundee have discovered a new antimalarial compound called cabamiquine, which could significantly simplify the treatment and prevention of malaria. The molecule is described as a novel drug-like compound that can be administered in a single dose.

Early-stage clinical trials indicate that when cabamiquine is used in combination with the existing drug pyronaridine, it is effective and maintains a favorable safety profile in both adults and adolescents. This breakthrough offers potential for streamlining dosing regimens globally, which is critical as malaria cases and deaths continue to rise due to increasing drug resistance.

The initial research was conducted in Dundee with funding from Medicines for Malaria Venture (MMV). Following these successful early results, the research team plans to pursue further development through larger clinical trials, including studies focused on pediatric patients.

Entities

Beatriz Baragana · Ian Gilbert · Medicines for Malaria Venture · University of Dundee

Claims

What the coverage asserts, and how many sources carry each claim.

[● 3 SOURCES] Researchers intend to pursue further development of the combination therapy in larger trials and among children. www.standard.co.uk · ca.news.yahoo.com · www.independent.co.uk
[● 3 SOURCES] Researchers at the University of Dundee discovered a new antimalarial compound named cabamiquine. www.standard.co.uk · ca.news.yahoo.com · www.independent.co.uk
[● 3 SOURCES] Cabamiquine is a novel drug-like molecule that can be administered in a single dose. www.standard.co.uk · ca.news.yahoo.com · www.independent.co.uk
[● 3 SOURCES] The discovery of cabamiquine was supported and funded by Medicines for Malaria Venture (MMV). www.standard.co.uk · ca.news.yahoo.com · www.independent.co.uk
[● 3 SOURCES] When combined with pyronaridine, cabamiquine is effective and has a favourable safety profile in adults and adolescents. www.standard.co.uk · ca.news.yahoo.com · www.independent.co.uk
[● 3 SOURCES] In 2024, there were an estimated 282 million malaria cases and 610,000 deaths worldwide. www.standard.co.uk · ca.news.yahoo.com · www.independent.co.uk

Sources

Antimalarial compound hailed as ‘exciting step forward’ in fight against disease [www.standard.co.uk]

29 days ago

New High-Resolution Mapping Reveals Where Malaria Persists in Senegal [www.worldpop.org]

27 days ago

Single dose malaria drug could simplify treatment worldwide in medical breakthrough [ca.news.yahoo.com]

29 days ago

Single dose malaria drug could simplify treatment worldwide in medical breakthrough [www.independent.co.uk]

29 days ago