University of the Sunshine Coast study links exercise to dementia prevention

Research conducted at the University of the Sunshine Coast’s Thompson Institute has identified a link between physical activity and the preservation of the hippocampus, a brain region critical for memory that typically shrinks with age. The study, published in the journal ‘Aging Cell’, highlights the role of a brain chemical called irisin.

Lead author Dr. Thomas Pace noted that older adults who exercise frequently exhibit higher levels of irisin in their blood. This chemical is associated with a larger hippocampus, particularly in subfields vital for memory. This represents the first time this specific biological pathway has been demonstrated in humans, offering potential insights into preventing the onset of Alzheimer’s disease.

To celebrate the findings and promote brain health, more than 200 seniors participated in a ‘hippocampus shuffle’ outdoor exercise class. Researchers, including Associate Professor Sophie Andrews, are now working to apply these findings to design lifestyle interventions, such as diet and exercise programs, to support healthy aging.