U.S. Adults Face Chronic Pain and Depression with New Health Guidance

In 2021, an estimated 20.9% of U.S. adults reported chronic pain, a prevalence higher than heart disease, cancer and diabetes combined. Among runners, about 79% experience pain during training, with conditions such as plantar fasciitis, arthritis and lingering injuries common. Experts advise distinguishing between soreness and injury, modifying training plans, and using evidence‑based strategies to manage pain without halting activity.

Approximately 9% of U.S. adults experience major depression each year, with higher lifetime rates in women. Functional medicine offers a patient‑centered approach that targets root causes through nutrition, lifestyle changes and advanced testing. Incorporating anti‑inflammatory diets like the Mediterranean pattern, along with personalized interventions, can improve mood, reduce inflammation and potentially lower reliance on medication.

Both pieces emphasize that informed, individualized plans—whether for running with chronic pain or managing depression—can help adults maintain health and quality of life.