USC researchers develop ultrasound technique to target solid tumors

CAR-T cell therapy solid tumors focused ultrasound cancer research USC Viterbi School of Engineering

Researchers at the USC Viterbi School of Engineering have developed a new technique using focused ultrasound to improve the effectiveness of CAR-T cell therapy against solid tumors. While CAR-T therapy has been a breakthrough for blood cancers by using engineered T-cells to identify and destroy malignant cells, it has historically struggled to target solid tumors due to a lack of clear markers.

The new method, described by researcher Tianze Guo, allows for the creation of a temporary marker on hard-to-reach tumors. The system works by detecting tumor signals, such as low oxygen levels, and utilizing focused ultrasound to make the tumors visible to the CAR-T cells.

Separately, discussions regarding stem cell therapy continue to highlight its potential in regenerative medicine, particularly for reducing chronic inflammation. However, experts note that while blood stem cell transplantation is an established clinical standard for diseases like leukemia, the regeneration of completely destroyed tissue remains inconsistent in practice.

Entities

Cleveland Clinic · Tianze Guo · USC Viterbi School of Engineering

Claims

What the coverage asserts, and how many sources carry each claim.

[● 2 SOURCES] Researchers have developed a method to provide hard-to-reach tumors with a temporary marker visible to CAR-T cells. www.mannheim24.de · www.tz.de
[● 2 SOURCES] The new system identifies tumor signals, such as low oxygen levels, and combines them with focused ultrasound. www.mannheim24.de · www.tz.de
[● 2 SOURCES] CAR-T cell therapy has previously been unsuccessful in treating solid tumors due to a lack of clear targets. www.mannheim24.de · www.tz.de
[● 2 SOURCES] Researchers at the USC Viterbi School of Engineering discovered a new approach using focused ultrasound to target solid tumors. www.mannheim24.de · www.tz.de
[● 2 SOURCES] CAR-T cell therapy involves adding a lab-made gene to a patient's T-cells to help them recognize and kill cancer cells. www.mannheim24.de · www.tz.de

Sources

5 Fakten zur Stammzelltherapie: Hoffnung oder Hype? [www.medicalblogs.de]

26 days ago

Neuer Ultraschall-Trick: Forscher zwingen aggressive Tumore, sich selbst für die Zerstörung zu markieren [www.mannheim24.de]

24 days ago

Neuer Ultraschall-Trick: Forscher zwingen aggressive Tumore, sich selbst für die Zerstörung zu markieren [www.tz.de]

24 days ago