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[HEALTH] · United Kingdom, United States · 3 sources

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Vitamin D linked to increased longevity and slower cellular aging

Recent research highlights the critical role of Vitamin D in long-term health and its potential connection to longevity. Studies indicate that low Vitamin D levels are associated with an increased risk of premature death from cardiovascular, respiratory, and neoplastic diseases. Specifically, a study of over 300,000 British adults found that those with levels below 25 nmol/l faced a 25 percent higher mortality risk.

Furthermore, a 2025 American study suggests that daily supplementation of 2,000 IU of Vitamin D may slow cellular aging. Researchers observed that participants taking daily doses experienced slower telomere shortening, an effect estimated to be equivalent to delaying age-related telomere loss by nearly three years. This effect was not observed with omega-3 fatty acids.

Dietary habits also play a significant role in Vitamin D efficacy. Because Vitamin D is fat-soluble, it is best absorbed when consumed with a meal containing fats, such as eggs, avocado, or yogurt, rather than with black coffee alone. While certain foods like legumes and spinach contain phytates that can affect mineral absorption, and high caffeine intake has been linked to lower Vitamin D levels, experts note that these do not directly block absorption but suggest the importance of a balanced diet for optimal supplementation.

Entities

German Cancer Research Center · Max Planck Institute for Biology of Ageing · Sebastian Grönke