Washington State University researchers link OCA2 gene to eye development

Researchers at Washington State University have discovered that the OCA2 gene, which is responsible for one of the most common forms of albinism, plays a broader role in development than previously understood. Using zebrafish embryos to conduct the study, scientists found that mutations in this gene caused unexpected changes in pigment cells, eye formation, and the activity of dozens of other genes.

The findings suggest that OCA2 influences biological processes beyond the production of melanin. If these processes are similar in humans, the research could help explain vision complications associated with albinism, such as impaired vision and involuntary eye movement, potentially guiding the search for new treatments.