WEHI researchers develop experimental malaria vaccine method

Researchers at the Melbourne-based institute WEHI have developed an experimental malaria vaccination method that could potentially turn mosquito bites into immune-boosting events. The study, published in the journal Science, has shown success in mice.

By using an experimental drug as a chemical vaccine, scientists can allow the malaria parasite to grow within the body before neutralizing it just before it causes disease. This process enables the body to build up essential antibodies and immune cells to defend against future infections.

Associate Professor Justin Boddey, a malaria researcher at WEHI, noted that the method aims to convert bites that spread malaria into vaccination events. This approach addresses limitations of current vaccines, which often require multiple doses and vary in effectiveness between 40 and 75 per cent.