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[HEALTH] · United States · 3 sources

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Weill Cornell Medicine study links stress hormone rhythms to obesity

Researchers at Weill Cornell Medicine have found that the timing of stress hormone fluctuations may play a significant role in weight gain, independent of caloric intake.

In a study involving mice, scientists disrupted the natural daily rhythm of stress hormones using corticosterone-releasing implants. While the average hormone levels remained largely within normal ranges, the timing of the peaks and troughs was altered. Despite consuming a standard diet, the mice with disrupted rhythms gained nearly as much fat over a 30-day period as mice fed a high-fat diet.

The findings suggest that the circadian rhythm of hormones like cortisol is a critical factor in metabolism, potentially explaining how lifestyle factors such as shift work, which can disrupt these rhythms, might contribute to obesity.

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Weill Cornell Medicine

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