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[HEALTH] · Congo - Kinshasa, Kenya, Nigeria, Uganda · 23 sources

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Part of situation: Bundibugyo Ebola outbreak and vaccine response (3 clusters)

WHO approves clinical trials for two new Ebola vaccines in DRC

Ebola outbreak Bundibugyo strain World Health Organization vaccine clinical trials Democratic Republic of the Congo

The World Health Organization (WHO) has recommended expanding clinical trials in the Democratic Republic of the Congo to include two new vaccine candidates specifically targeting the Bundibugyo strain of the Ebola virus. The two candidates are ChAdOx1 BDBV, developed by the University of Oxford and the Serum Institute of India, and mRNA-1469, developed by Moderna.

The current outbreak, which was officially declared in May, is being driven by the Bundibugyo strain, for which there are currently no approved vaccines or specific treatments. While the Ervebo vaccine is being used in ongoing trials, it was developed for the Zaire strain and its effectiveness against Bundibugyo is unconfirmed.

According to the Africa Centres for Disease Control and Prevention (Africa CDC), the epidemic has resulted in 10,444 confirmed cases and more than 5,300 deaths, with the vast majority occurring in the DRC. The fatality rate is reported to exceed 50 percent. Cases have also been confirmed in Kenya, Uganda, and Nigeria. The clinical trials are being led by the DRC’s National Institute for Biomedical Research, with support from the WHO and other international partners. Researchers expect to obtain initial results from these vaccine trials in early 2027.

Entities

Democratic Republic of the Congo · Moderna · Tedros Adhanom Ghebreyesus · University of Oxford · World Health Organization

Claims

What the coverage asserts, and how many sources carry each claim.

Sources

La OMS aprueba ensayos clínicos de dos nuevas vacunas contra el ébola [dominicanodigital.com]
Ebola outbreak: WHO backs two new vaccine trials [nax.today]
OMS recomenda testes de novas vacinas contra Ebola no Congo [brasilemfolhas.com.br]
WHO schválila klinické skúšky dvoch nových vakcín proti ebole - Svet - Správy - pravda.sk [www.pravda.sk]
OMS inclui duas vacinas experimentais em teste contra Ebola no Congo | CNN Brasil [www.cnnbrasil.com.br]
Ebola Outbreak: WHO Recommends Clinical Trials for Two New Vaccines in DR Congo [world-today-journal.com]
WHO approves trials for two new Ebola vaccines | Barbados Gazette – Barbados & Caribbean News [barbadosgazette.com]
WHO thúc đẩy thử nghiệm vaccine mới đối phó Ebola chủng Bundibugyo [baoquocte.vn]
How AI is helping WHO combat the fastest-growing Ebola outbreak [k24.digital]
Núcleo Comunicación del Sureste [ncscampeche.com]
Two New Ebola Vaccines Get WHO Approval for Trials [newscentraltv.com]
WHO recommends 2 new Ebola vaccine candidates for DRC trial [realnewsmagazine.net]
La OMS respalda ensayos de 2 nuevas vacunas contra el brote de ébola [es.euronews.com]
WHO Greenlights Two Ebola Bundibugyo Virus Vaccine Candidates For Phase 2/3 Trials [healthpolicy-watch.news]
WHO schválila klinické skúšky dvoch nových vakcín proti ebole. Epidémia v Afrike má vyše 5300 obetí [hnonline.sk]
WHO approves trials for two new Ebola vaccines - Guyana Inquirer – Daily Guyana News [guyanainquirer.com]
Oms sostiene la sperimentazione di due nuovi vaccini contro l'epidemia di Ebola in Africa [it.euronews.com]
OMS aprobă studiile clinice pentru două noi vaccinuri împotriva Ebola [www.stiripesurse.ro]
Ebolavaccins: WHO beveelt twee kandidaten aan voor proef [tpo.nl]
WHO Approves Two New Vaccine Candidates For Ebola Trials - Voice of Nigeria [von.gov.ng]
Do boja s ebolou pribudnú dve nové vakcíny, epidémia má už vyše 5 300 obetí, oznámila WHO - SITA.sk [sita.sk]
Wereldgezondheidsorganisatie staat gebruik van twee nieuwe ebolavaccins toe [nos.nl]
WHO approves clinical trials on two new Ebola vaccines [punchng.com]