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2 clusters · 4 sources · 3 days · First seen · Last updated
Advancements in neural mapping and imaging technology
Overview
Recent advancements in neuroscience have focused on improving the precision and speed of mapping and observing neuronal activity.
Initial developments included the reconstruction of a complete connectome for a Platynereis dumerilii larva, identifying over 9,000 cells and 202 distinct neuron types. Concurrently, researchers at the University of Colorado developed the Opto2P-FCM, a miniature microscope designed to observe and control individual brain cells in real-time during natural movement.
Building on these imaging capabilities, researchers at MIT developed a high-speed microscopy technique to record electrical activity across the entire brain of zebrafish. By utilizing modified light-sheet microscopy and remote focal scrambling, this method allows for millisecond-scale tracking of electrical potential. This approach provides a more direct observation of neural processes than traditional calcium imaging, which is limited by slower intracellular calcium flows.
Entities
Massachusetts Institute of Technology · Ed Boyden · McGovern Institute for Brain Research · University of Colorado · Nature Methods
Timeline
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29 days ago
[TECHNOLOGY] 2 sourcesMIT researchers develop high-speed microscope to track brain activityMIT researchers have developed a high-speed microscopy technique to track electrical neural activity in zebrafish at millisecond resolution, surpassing the speed of traditional calcium imaging.
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about 1 month ago
[TECHNOLOGY] 2 sourcesNeuroscience advances in cellular mapping and real-time brain imagingNeuroscientists have reconstructed the complete cellular connectome of a marine larva and developed a miniature microscope to observe real-time neuronal activity in moving animals.
Sources
diariodelsur.com.co · quotidianodibari.it · sudefuturi.it · web.eldia.es