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2 clusters · 5 sources · 19 days · First seen · Last updated

Candida auris research and survival mechanisms

Overview

Scientific research has identified several ways the fungal pathogen Candida auris evades immune responses and medical treatments. Researchers at the University of California, San Francisco discovered that the fungus triggers a specific immune response that facilitates colonization of hair follicles, contributing to its ability to infect healthy individuals and pose a threat to immunocompromised patients.

Further studies published in Nature Communications revealed that the fungus can create multiple copies of its entire genome, a mechanism that increases the likelihood of developing mutations to evade antifungal drugs.

While Candida auris has caused outbreaks in over 60 countries and is classified by the World Health Organization as a critical-priority pathogen, researchers are also investigating external contributing factors. Some studies suggest that climate change and rising global temperatures may assist the fungus in adapting to the human body, while the use of fungicides in agriculture remains under investigation.

Entities

Candida auris · University of California, Irvine · University of California, San Francisco · World Health Organization · University of Würzburg

Timeline

  1. [HEALTH] 2 sources
    Researchers identify survival mechanism in deadly Candida auris fungus

    Scientists have discovered that the drug-resistant fungus Candida auris can replicate its genome to evade treatment, while researchers suggest climate change may drive its ability to infect humans.

  2. [HEALTH] 3 sources
    Medical researchers uncover mechanisms of Candida auris and liver protection via inulin

    Scientists have uncovered how the superbug Candida auris colonizes skin via hair follicles and discovered that the fiber inulin can protect the liver from fructose damage by altering gut bacteria.

Sources

mreza.bug.hr · myfoxatlanta.com · newswise.com · vecernji.ba · vecernji.hr