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2 clusters · 2 sources · 30 days · First seen · Last updated

MD Anderson cancer treatment research findings

Overview

Researchers at the University of Texas MD Anderson Cancer Center have published findings regarding physiological complications associated with cancer and its treatments.

Initial research indicated that colorectal tumors may cause peripheral nerve damage through inflammation and fat metabolism alterations before chemotherapy begins. This suggests that nerve damage may be latent and caused by the cancer itself, potentially making nerves more susceptible to injury during subsequent treatments.

Subsequent studies identified a role for B cell dysregulation in triggering and sustaining colitis, a side effect of immune checkpoint inhibitors used in immunotherapy. The research suggests that changes in circulating B cell activity could serve as a blood-based biomarker to identify patients at risk of developing this inflammatory condition before symptoms appear.

Entities

MD Anderson Cancer Center · Andrew Shepherd · Roza Nurieva · University of Texas MD Anderson Cancer Center · Nature Communications

Timeline

  1. 5 days ago

    [HEALTH] 2 sources
    MD Anderson researchers identify B cell role in immunotherapy-related colitis

    Researchers have found that B cells may trigger immunotherapy-related colitis, offering a potential blood-based biomarker to identify at-risk cancer patients before symptoms emerge.

  2. about 1 month ago

    [HEALTH] 3 sources
    MD Anderson researchers find colorectal cancer may damage nerves before chemotherapy

    A study from MD Anderson Cancer Center suggests colorectal tumors can damage peripheral nerves through inflammation before chemotherapy begins, potentially increasing vulnerability to treatment-induced injury.

Sources

ma-clinique.fr · news-medical.net