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Microbiome and reproductive health research

Updated 3 times since CLSTR started tracking revisions of this situation.

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2026-08-12 15:12 UTC → 2026-08-22 12:44 UTC · added removed

Recent medical research has identified several links between microbiomes and reproductive health. A study involving couples in Denmark and Sweden Sweden, published in The Lancet Obstetrics, Gynaecology & Women's Health, found that bacterial imbalance, or dysbiosis, in male semen is associated with lower live-birth rates and increased pregnancy loss risk during IVF treatments. Specifically, among IVF couples, 57% of those with semen dysbiosis had a baby compared with 85% without the imbalance, and miscarriage risk was approximately 26 percentage points higher when the male partner had the imbalance. Parallel research has focused on the female endometrial microbiome. Studies Studies, including investigations by scientists at the University of Beijing published in Cell Host & Microbe, indicate that a decline in the bacterium Lactobacillus gasseri is associated with advancing reproductive age in women over 35. age. Experimental data involving human cells and mice suggests that supplementing this bacterium or its derivatives may improve uterine conditions and embryo implantation. implantation, potentially offering a new treatment to boost fertility in women over 35. Additionally, research published in Diabetologia has identified a correlation between endometriosis and an increased risk of type 2 diabetes, suggesting chronic inflammation may be a contributing factor. diabetes. The ARCHES study, which analyzed health records from approximately three million women in the Utah Population Database between 1996 and 2021, Database, found that women diagnosed with endometriosis face a 46% higher risk of developing type 2 diabetes. The study noted that the association varies by subtype: women with superficial peritoneal endometriosis showed a 67% increased risk, while those with ovarian endometriosis showed a 61% increased risk. The strongest associations were observed in extrapelvic endometriosis. Researchers emphasized that the study shows an association rather than a direct cause-and-effect relationship, highlighting a need for further research into biological mechanisms and early metabolic screening, particularly as increased risks were observed even in women without obesity.

Versions

  1. 2026-08-22 12:44 UTC Microbiome and reproductive health research
  2. 2026-08-12 15:12 UTC Microbiome and reproductive health research
  3. 2026-08-11 23:22 UTC Microbiome and reproductive health research
  4. 2026-08-11 06:51 UTC Microbiome and reproductive health research

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