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2 clusters · 2 sources · 21 days · First seen · Last updated

Research into cancer-related extracellular vesicles

Overview

Scientific research has identified new roles for extracellular vesicles in cancer progression. In Italy, University of Milan researchers discovered a mechanism in multiple myeloma where vesicles transport Jagged1 and Jagged2 molecules to activate Notch receptors. This process allows tumor cells to signal at a distance, promoting blood vessel formation and bone resorption.

Concurrently, researchers at McGill University identified a specific type of extracellular vesicle called ‘MoVes’ (motile vesicles). These are released by migrating cancer cells and carry genetic material, including mutations, into the surrounding environment. These findings suggest that studying these vesicles may offer new ways to understand metastasis, chemoresistance, and potential therapeutic interventions.

Entities

Domenica Giannandrea · Leukemia · Montreal · Raffaella Chiaramonte · Nature Cell Biology

Timeline

  1. [HEALTH] 2 sources
    McGill University researchers discover new cancer-related vesicles

    McGill University scientists have discovered ‘MoVes’, a new type of extracellular vesicle that cancer cells release while moving, potentially explaining how they spread genetic material and facilitate disease.

  2. [HEALTH] 2 sources
    University of Milan researchers identify new multiple myeloma mechanism

    University of Milan researchers discovered that extracellular vesicles carrying Jagged1 and Jagged2 molecules help multiple myeloma cells spread their influence and promote tumor growth at a distance.

Sources

novini247.com · reporter.mk