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2 clusters · 8 sources · 1 days · First seen · Last updated
Rheumatoid arthritis research and treatment developments
Overview
Medical research into rheumatoid arthritis (RA) has highlighted both long-term management strategies and potential new therapeutic compounds. Long-term data from the ARCTIC trial indicates that a ‘treat-to-target’ strategy—adjusting treatments to achieve specific goals like remission—can result in significant health benefits, with 82% of assessed patients reaching remission ten years after diagnosis.
Simultaneously, studies are investigating the efficacy of natural plant compounds. Research published in the journal Engineering identified obakulactone (OL), extracted from Phellodendri cortex bark, as a substance that may reduce joint swelling and protect cartilage by influencing lipid metabolism. Laboratory experiments on rat models and cell cultures suggest that this compound helps restore balance to unsaturated fatty acids and shifts macrophage behavior from an aggressive inflammatory state toward tissue repair.
Entities
Queen Mary University of London · Ministry of Economy and Finance · Italy · National Institute for Health and Care Research · Afferent Medical Solutions
Timeline
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[HEALTH] 7 sourcesEar nerve stimulation device tested for hypertension treatment
A clinical trial of a non-invasive ear stimulation device showed encouraging blood pressure reduction in patients with severe hypertension, though overall results across all participants were not significant.
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[HEALTH] 2 sourcesRheumatoid arthritis research highlights early treatment and natural compounds
New studies show that early 'treat-to-target' strategies can lead to long-term remission in rheumatoid arthritis, while the plant compound obakulactone shows promise in reducing inflammation in animal models.
Sources
farmacoecura.it · knowridge.com · leitv.it · sciencedaily.com · soldionline.it · thewom.it · webboh.it · world-today-news.com