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Scientific research into diabetes subtypes

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2026-09-06 13:21 UTC → 2026-09-08 19:39 UTC · added ~~removed~~

Recent scientific research suggests that diabetes may not be a uniform condition but rather a collection of biologically distinct subtypes. In France, researchers identified four immune profiles in type 2 diabetes patients: Severe Inflammatory Diabetes (SIND), Mild Inflammatory Diabetes (MIND), Lymphocyte-Rich Diabetes (LYRD), and Lymphocyte-Deficient Diabetes (LYDD). Using blood tests to identify these profiles could allow for personalized medicine and the prediction of cardiovascular and renal complications up to five years in advance. Simultaneously, a ~~genetic~~ large-scale international genome-wide association study (GWAS) conducted in the United States and the United Kingdom indicates that type 1 diabetes may consist of at least two distinct ~~diseases.~~ subtypes. By analyzing genetic profiles HLA-DR3 and ~~HLA-DR4,~~ HLA-DR4 in a study of 9,091 individuals with type 1 diabetes, researchers found that the ~~biological mechanisms and~~ genetic differences between these groups are significant. Findings published in the journal Diabetologia suggest these differences are as ~~significant~~ substantial as the distinction between schizophrenia and bipolar disorder. Distinguishing between these subtypes could lead to more personalized treatments and a deeper understanding of the biological mechanisms driving the autoimmune destruction of pancreatic beta cells. These findings across both type 1 and type 2 diabetes point toward a future of more precisely tailored therapeutic approaches.

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