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CDC reports high neuroinvasive West Nile rates and Naegleria fowleri risks
Recent health data from the Centers for Disease Control and Prevention (CDC) highlights the risks associated with specific infectious diseases in the United States.
Regarding West Nile virus, the CDC has reported 504 human cases across 41 states this year. Approximately 72 percent of these, or 363 cases, are neuroinvasive, meaning the virus reaches the brain or spinal cord. While the total number of cases is currently lower than at the same point in 2025, the proportion of severe, neuroinvasive cases is higher than last year's 64 percent. Health officials note that mild cases often go unreported, meaning these figures represent the most severe portion of infections.
Separately, an analysis of Naegleria fowleri infections shows that while the amoeba is rare, it remains extremely dangerous. Between 1937 and 2025, the CDC documented 180 infections in the U.S., typically resulting in primary amebic meningoencephalitis (PAM), a brain infection that is almost always fatal. Texas and Florida have reported the highest frequency of cases, followed by Virginia and California. The infection typically enters through the nose and progresses rapidly.
Entities
Annenberg Public Policy Center · Centers for Disease Control and Prevention · University of Pennsylvania