Common medications linked to side effects and blood pressure interference

Medical experts and new clinical guidelines are highlighting how common medications can cause unintended side effects or interfere with existing treatments for chronic conditions.

Regarding cholesterol management, pharmacist Dipa Kamdar notes that while statins are vital for reducing heart attack and stroke risks, they can cause side effects such as headaches, digestive issues, and dizziness. More serious, though rarer, complications include liver inflammation and muscle problems like myopathy or rhabdomyolysis. Additionally, certain foods like grapefruit can influence the effectiveness of statins.

In the context of hypertension, the 2025 AHA/ACC guidelines identify several substances that can raise blood pressure or reduce the efficacy of antihypertensive drugs. Approximately 20% of adults with hypertension regularly use over-the-counter medications that may interfere with their treatment. Nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen and naproxen, are specifically noted for their potential to increase blood pressure through sodium and water retention.