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[HEALTH] · Congo - Kinshasa · 52 sources

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DR Congo launches Ebola vaccine trial in Ituri province

Health authorities in the Democratic Republic of the Congo have launched an experimental vaccination campaign in Bunia, Ituri province, to combat a rapidly spreading Ebola outbreak caused by the Bundibugyo strain. The campaign, supported by the World Health Organization and Doctors Without Borders (MSF), utilizes the Ervebo vaccine. While Ervebo was originally licensed for the Zaire strain, researchers are conducting the BRAVO clinical trial to assess its potential cross-protection against the Bundibugyo variant.

The trial aims to monitor approximately 20,000 frontline workers in the Ituri and North Kivu provinces over a period of nine to 12 months. This follows an initial allocation of 70,000 doses to the DRC, with 50,000 intended for frontline responders and 20,000 reserved for the Phase 3 study. As of mid-September, over 3,700 people had been vaccinated across various provinces.

The epidemic has reached significant proportions, with the DRC government reporting 7,541 confirmed cases and 3,639 deaths. Data from UN Women highlights a disproportionate impact on women and girls, who account for approximately 55% of confirmed cases and over 60% of cases among adolescents aged 10 to 17, often due to their roles as primary caregivers in communities.

Entities

ALIMA · Africa CDC · Bundibugyo Ebola virus · Democratic Republic of the Congo · Doctors Without Borders · Ervebo · Gaby Kasongo Mulumba · Ituri · Médecins Sans Frontières · ONU Femmes · UN Women · World Health Organization

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