Late-night eating linked to increased risk of liver disease

Research involving approximately 200,000 participants across three studies indicates that consuming meals or snacks late at night is associated with a significantly higher risk of developing liver diseases. Findings published in Clinical Gastroenterology and Hepatology suggest that eating after dinner or immediately before sleep can increase the risk of metabolic dysfunction-associated steatotic liver disease (MASLD) or cirrhosis by 20 to 30 percent.

Lead author Dr. Robert Wilechansky of Oregon Health and Science University (OHSU) noted that the liver is closely aligned with the body’s circadian rhythm. Experts suggest that the timing of food consumption is a critical factor in metabolic health, independent of the specific composition of the food.

To support liver health and improve sleep quality, nutritionists recommend eating a light, nutrient-dense dinner consisting of vegetables, lean proteins, and fiber at least two to three hours before bedtime. Avoiding caffeine, high-sugar foods, and heavy, spicy, or salty meals late in the evening may also help maintain stable blood sugar levels and prevent sleep disturbances.