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Melatonin research challenges heart failure risk concerns
Recent scientific research is reshaping the debate regarding the safety of melatonin, a popular sleep aid. In late 2025, a study presented at the American Heart Association Scientific Sessions raised concerns that long-term melatonin use might increase the risk of heart failure. That study, led by Dr. Ekenedilichukwu Nnadi, analyzed health data from 130,828 adults with chronic insomnia.
However, newer research provides a different perspective. Randomized controlled studies have not yet confirmed that melatonin causes heart damage. Furthermore, a recent meta-analysis suggests that the supplement may even offer potential positive effects for certain patient groups.
Entities
American Heart Association · Ekenedilichukwu Nnadi · Premium Medical Circle
Claims
What the coverage asserts, and how many sources carry each claim.
- [● 4 SOURCES] Randomized controlled studies have not confirmed that melatonin causes heart damage. www.leinetal24.de · www.hna.de · www.mannheim24.de · www.merkur.de
- [● 4 SOURCES] A 2025 study presented at the American Heart Association Scientific Sessions suggested a link between long-term melatonin use and increased heart failure risk. www.leinetal24.de · www.hna.de · www.mannheim24.de · www.merkur.de
- [● 4 SOURCES] A recent meta-analysis indicates potential positive effects of melatonin in specific patient groups. www.leinetal24.de · www.hna.de · www.mannheim24.de · www.merkur.de