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3 clusters · 10 sources · 23 days · First seen · Last updated
Melatonin use and heart failure risk study
Overview
A preliminary observational study presented at the American Heart Association Scientific Sessions suggested a potential link between long-term melatonin use and an increased risk of heart failure. Analyzing over 130,000 adults, researchers found that those using the supplement for at least 12 months had a higher probability of developing heart failure compared to non-users. Lead researcher Ekenedilichukwu Nnadi noted that ‘melatonin supplements might not be as harmless as is commonly believed.’
Subsequent reporting emphasized that the study does not prove a cause-and-effect relationship. The observed association may result from ‘confounding by indication,’ meaning the underlying conditions requiring melatonin—such as anxiety, depression, or chronic insomnia—could be the actual drivers of cardiovascular risk. Additionally, the findings were presented as a conference abstract and had not yet undergone full peer review.
Recent scientific research has begun to reshape the debate regarding melatonin safety. While the initial study raised concerns, newer randomized controlled studies have not confirmed that melatonin causes heart damage. Furthermore, a recent meta-analysis suggests that the supplement may offer potential positive effects for certain patient groups.
Entities
American Heart Association · Ekenedilichukwu Nnadi · Premium Medical Circle
Claims
What the coverage asserts, and how many sources carry each claim.
- [● 4 SOURCES] A 2025 study presented at the American Heart Association Scientific Sessions suggested a link between long-term melatonin use and increased heart failure risk. www.leinetal24.de · www.hna.de · www.mannheim24.de · www.merkur.de
- [● 4 SOURCES] Randomized controlled studies have not confirmed that melatonin causes heart damage. www.leinetal24.de · www.hna.de · www.mannheim24.de · www.merkur.de
- [● 4 SOURCES] A recent meta-analysis indicates potential positive effects of melatonin in specific patient groups. www.leinetal24.de · www.hna.de · www.mannheim24.de · www.merkur.de
Timeline
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about 7 hours ago
[HEALTH] 6 sourcesMelatonin research challenges heart failure risk concernsNew research challenges previous concerns that long-term melatonin use increases heart failure risk, with recent studies finding no confirmed harm and potential benefits for some groups.
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11 days ago
[HEALTH] 2 sourcesMelatonin use linked to heart failure risks in observational studyA study suggests a potential link between long-term melatonin use and heart failure, though researchers warn it may be due to underlying sleep disorders rather than the supplement itself.
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23 days ago
[HEALTH] 2 sourcesMelatonin use linked to increased heart failure riskA study suggests long-term melatonin use for insomnia may increase the risk of heart failure by approximately 90% over five years, according to research presented to the American Heart Association.
Sources
actualidad.rt.com · ad-hoc-news.de · fehmarn24.de · hna.de · infinitynews.it · leinetal24.de · mannheim24.de · merkur.de · microbiologiaitalia.it · precision.com.do
This summary has been updated 1 time: see revision history