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Moderna's Bundibugyo Ebola Vaccine Enters Phase 1 Trial in Canada
Health Canada has authorized Moderna to begin a Phase 1 clinical trial of its mRNA‑1469 vaccine targeting the Bundibugyo strain of Ebola. The first participant was dosed on 3 August at a site in Truro, Nova Scotia, with the trial also taking place in Halifax and Toronto and enrolling about 80 healthy adult volunteers. The study will assess safety, tolerability and the immune response generated by the vaccine.
The trial is supported by the Coalition for Epidemic Preparedness Innovations (CEPI), which has pledged up to $50 million for pre‑clinical work, the Phase 1 study and manufacturing of additional doses. The effort responds to the ongoing outbreak in the Democratic Republic of the Congo, where the World Health Organization and Africa CDC have declared a public‑health emergency. As of 1 August, the outbreak has produced roughly 3,748 confirmed cases and 1,657 deaths.
Moderna has said that, if the vaccine is licensed, it will make at least 500,000 doses available to low‑ and middle‑income countries under access‑pricing terms.
Entities
Bundibugyo ebolavirus · Coalition for Epidemic Preparedness Innovations · Coalition for Epidemic Preparedness Innovations (CEPI) · Democratic Republic of Congo · Democratic Republic of the Congo · Hamilton Bennett · Health Canada · Moderna · Moderna Inc. · mRNA-1469 · mRNA‑1469 · mRNA‑1469 (Bundibugyo Ebola vaccine)
Claims
What the coverage asserts, and how many sources carry each claim.
- [● 13 SOURCES] Moderna plans to make at least 500,000 doses available to low‑ and middle‑income countries under access‑pricing terms if the vaccine is licensed. kelo.com · wxerfm.com · ca.news.yahoo.com · wkzo.com · www.dgabc.com.br · +7 more
- [● 11 SOURCES] Moderna began its first human trial of an experimental vaccine against Bundibugyo ebolavirus. kelo.com · wxerfm.com · ca.news.yahoo.com · wkzo.com · www.dgabc.com.br · +5 more
- [● 16 SOURCES] The World Health Organization and Africa CDC have declared the outbreak a public‑health emergency. kelo.com · wxerfm.com · ca.news.yahoo.com · battlefordsnow.com · kitchener.citynews.ca · +10 more
- [● 13 SOURCES] The Democratic Republic of the Congo outbreak has 3,748 confirmed cases and 1,657 deaths as of early August. kelo.com · wxerfm.com · ca.news.yahoo.com · wkzo.com · www.globaldiasporanews.com · +7 more
- [● 10 SOURCES] The trial will enroll about 80 healthy adults at three sites in Canada. kelo.com · wxerfm.com · ca.news.yahoo.com · battlefordsnow.com · kitchener.citynews.ca · +4 more
- [● 13 SOURCES] The vaccine candidate is called mRNA‑1469. kelo.com · wxerfm.com · ca.news.yahoo.com · wkzo.com · www.dgabc.com.br · +7 more
- [● 16 SOURCES] CEPI pledged up to $50 million to fund pre‑clinical work, the Phase 1 trial and manufacturing of additional doses. kelo.com · wxerfm.com · ca.news.yahoo.com · wkzo.com · www.dgabc.com.br · +10 more
- [● 19 SOURCES] Health Canada authorized the Phase 1 trial on July 30. kelo.com · wxerfm.com · ca.news.yahoo.com · battlefordsnow.com · kitchener.citynews.ca · +13 more
- [● 17 SOURCES] The trial will enroll about 80 healthy adults at three Canadian sites – Truro, Halifax and Toronto. www.globaldiasporanews.com · battlefordsnow.com · kitchener.citynews.ca · larongenow.com · vancouver.citynews.ca · +11 more
- [● 6 SOURCES] The Bundibugyo Ebola outbreak in the Democratic Republic of Congo has 3,748 confirmed cases and 1,657 deaths as of 1 August. www.globaldiasporanews.com · kelo.com · wkzo.com · wxerfm.com · www.dgabc.com.br · +1 more
- [● 13 SOURCES] The first volunteers received the vaccine dose on Monday. battlefordsnow.com · kitchener.citynews.ca · larongenow.com · vancouver.citynews.ca · thesudantimes.com · +7 more
- [● 9 SOURCES] The World Health Organization and Africa CDC have declared the outbreak a public‑health emergency of international concern. www.globaldiasporanews.com · nannews.ng · kelo.com · www.dgabc.com.br · gr.euronews.com · +4 more