PDRN ingredient trends in South Korean skincare

Polydeoxyribonucleotide (PDRN) has emerged as a significant trend in South Korean skincare, transitioning from clinical injectable treatments to consumer cosmetic products. Originally used in dermatological settings to support skin recovery, hydration, and elasticity, the ingredient is now being formulated into serums, ampoules, and masks.

Brands such as IOPE, under the Amorepacific umbrella, are advancing this trend through high-tech delivery systems and alternative sourcing. For instance, IOPE has developed BluePDRN™, a proprietary version derived from algae rather than the traditional salmon-derived sources. This innovation aims to provide wound-closure performance comparable to clinical versions while offering a consumer-friendly application for repairing the skin barrier and addressing irritation or dehydration.