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Personalized elimination diets alter gut microbiome in migraine patients
A randomized controlled trial published in Frontiers in Nutrition suggests that personalized elimination diets based on food-specific immunoglobulin G (IgG) can influence the gut-brain axis in adults with migraines.
The 12-week study, which involved 98 patients, found that adhering to the elimination diet was associated with changes in gut microbial composition and diversity. Researchers also observed a decrease in serum zonulin, a marker linked to intestinal permeability.
Additionally, the trial reported reductions in inflammatory biomarkers, specifically interleukin-6 (IL-6) and calcitonin gene-related peptide (CGRP). These findings indicate that targeted dietary interventions may help improve migraine symptoms and related sleep disturbances.
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- [● 2 SOURCES] Targeted dietary elimination may be linked to improved migraine symptoms and comorbid sleep disturbances. ma-clinique.fr · www.news-medical.net
- [● 2 SOURCES] The elimination diet led to a decrease in serum zonulin levels, a marker of intestinal permeability. ma-clinique.fr · www.news-medical.net
- [● 2 SOURCES] The trial previously reported reduced concentrations of interleukin-6 (IL-6) and calcitonin gene-related peptide (CGRP). ma-clinique.fr · www.news-medical.net
- [● 2 SOURCES] A 12-week randomized controlled trial studied the effects of IgG-guided elimination diets on gut microbiota and serum zonulin in migraine patients. ma-clinique.fr · www.news-medical.net
- [● 2 SOURCES] Adherence to the elimination diet was associated with changes in the composition and diversity of gut microbial populations. ma-clinique.fr · www.news-medical.net