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Mass General Brigham patient sets record with 271-day pig kidney transplant
A 66-year-old man, Tim Andrews, has set a medical record by living for 271 days with a genetically modified pig kidney. The transplant, performed in January 2025 at Mass General Brigham in Boston, allowed Andrews to live without dialysis for nearly nine months, providing a critical bridge while he awaited a human organ.
The pig kidney was developed by the biotech company eGenesis and underwent 69 genomic modifications. These changes included removing pig proteins to prevent immune rejection and adding seven human genes to improve compatibility. Researchers also inactivated porcine endogenous retroviruses to mitigate infection risks. During the transplant period, no pig-borne pathogens were detected in the patient.
The porcine organ eventually failed and was removed in October 2025. Following a brief 82-day period back on dialysis, Andrews successfully received a kidney from a deceased human donor in January 2026, which is currently functioning well.
Medical experts, including Leonardo Riella, suggest this success demonstrates how xenotransplantation can serve as a vital temporary solution for the millions of people worldwide facing organ shortages. In the United States alone, approximately 100,000 people are on transplant waiting lists.
Entities
Harvard Medical School · Leonardo Riella · Mass General Brigham · Mike Curtis · The Lancet · Tim Andrews · Yucatan miniature pig · eGenesis
Claims
What the coverage asserts, and how many sources carry each claim.
- [● 3 SOURCES] The average survival rate for patients on dialysis is approximately five years. hotnews.ro · newsweek.ro · unimedia.info
- [DISPUTED] Tim Andrews received the pig kidney transplant on January 25, 2025. unimedia.info · bccnews.com.tw · ubirataonline.com.br · www.flash.gr · www.ithome.com · +33 more
- [DISPUTED] Tim Andrews received a human kidney transplant in January 2026. unimedia.info · fjala.al · acnews.hu · www.fanpage.it · elineanoticias.com · +16 more
- [● 37 SOURCES] The pig kidney was removed in October 2025 after it ceased to function. unimedia.info · bccnews.com.tw · www.ithome.com · fjala.al · ubirataonline.com.br · +31 more
- [● 13 SOURCES] Approximately 100,000 people in the US are waiting for a kidney transplant. hotnews.ro · newsweek.ro · fjala.al · tob.news · bccnews.com.tw · +8 more
- [● 27 SOURCES] The transplant provided hope and allowed the patient to avoid dialysis for several months. hotnews.ro · newsweek.ro · unimedia.info · fjala.al · tob.news · +22 more
- [● 45 SOURCES] A genetically modified pig kidney functioned in a human recipient for 271 days. hotnews.ro · newsweek.ro · unimedia.info · elineanoticias.com · tob.news · +39 more
- [● 21 SOURCES] Tim Andrews underwent 82 days of dialysis after the pig kidney was removed. unimedia.info · bccnews.com.tw · www.ithome.com · fjala.al · jurnalul.ro · +15 more
- [● 39 SOURCES] The medical team at Mass General Brigham published findings on the case in the journal The Lancet. elineanoticias.com · bccnews.com.tw · ubirataonline.com.br · ca.news.yahoo.com · www.ithome.com · +33 more
- [● 8 SOURCES] No pig-borne pathogens or viruses were detected in the patient during the transplant period. elineanoticias.com · ca.news.yahoo.com · www.ithome.com · www.tothemaonline.com · bccnews.com.tw · +3 more
- [● 14 SOURCES] The pig kidney underwent 69 genomic modifications, including the removal of pig genes and the addition of seven human genes. bccnews.com.tw · www.ithome.com · time.news · www.flash.gr · jurnalul.ro · +8 more
- [● 14 SOURCES] The pig kidney failed due to damage in the blood vessels and inflammation after approximately six months. elineanoticias.com · bccnews.com.tw · ubirataonline.com.br · ca.news.yahoo.com · www.ithome.com · +9 more