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[HEALTH] · United States · 92 sources

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Mass General Brigham patient sets record with 271-day pig kidney transplant

A 66-year-old man, Tim Andrews, has set a medical record by living for 271 days with a genetically modified pig kidney. The transplant, performed in January 2025 at Mass General Brigham in Boston, allowed Andrews to live without dialysis for nearly nine months, providing a critical bridge while he awaited a human organ.

The pig kidney was developed by the biotech company eGenesis and underwent 69 genomic modifications. These changes included removing pig proteins to prevent immune rejection and adding seven human genes to improve compatibility. Researchers also inactivated porcine endogenous retroviruses to mitigate infection risks. During the transplant period, no pig-borne pathogens were detected in the patient.

The porcine organ eventually failed and was removed in October 2025. Following a brief 82-day period back on dialysis, Andrews successfully received a kidney from a deceased human donor in January 2026, which is currently functioning well.

Medical experts, including Leonardo Riella, suggest this success demonstrates how xenotransplantation can serve as a vital temporary solution for the millions of people worldwide facing organ shortages. In the United States alone, approximately 100,000 people are on transplant waiting lists.

Entities

Harvard Medical School · Leonardo Riella · Mass General Brigham · Mike Curtis · The Lancet · Tim Andrews · Yucatan miniature pig · eGenesis

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6 days ago
6 days ago
7 days ago
El riñón que vino del cerdo [www.diariodealmeria.es]
7 days ago