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[HEALTH] · Denmark · 3 sources

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University of Copenhagen study links diabetes medication non-adherence to higher stroke risk

A study conducted by the University of Copenhagen, published in The Lancet Regional Health – Europe, has found that irregular adherence to type 2 diabetes medication significantly increases the risk of heart attack and stroke.

Led by Jordi Merino from the Novo Nordisk Foundation Center for Basic Metabolic Research, the research analyzed data from 79,510 adults who were diagnosed with type 2 diabetes and began non-insulin treatments between 2005 and 2012. The study tracked pharmacy data over a 10-year period.

Researchers identified three distinct groups: 41% of patients followed their treatment regularly, approximately 33% showed moderate adherence, and 26% discontinued treatment early or had low continuous adherence. The findings indicate that those who did not take their medication regularly faced a 27% higher risk of serious cardiovascular events. Furthermore, low adherence was associated with a 45% increase in the risk of ischemic heart disease.

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Jordi Merino · Novo Nordisk Foundation Center for Basic Metabolic Research · The Lancet Regional Health – Europe · University of Copenhagen

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