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Caloric restriction and age-related inflammation research

Overview

Research indicates that moderate caloric restriction may reduce chronic inflammation associated with aging. Studies involving participants who reduced energy intake by approximately 14 percent over two years showed lower levels of C3a, a protein fragment in the complement system of the innate immune response.

Findings from the Yale School of Medicine suggest that this reduction in C3a is a direct result of caloric restriction rather than being solely dependent on weight loss or the reduction of fat tissue. Because aging is linked to increased C3 production, particularly in visceral white adipose tissue, scientists suggest these discoveries could eventually lead to therapies that mimic the anti-inflammatory benefits of dietary restriction.

Entities

Yale School of Medicine · Nature Aging · C3a protein

Timeline

  1. [HEALTH] 3 sources
    Yale researchers identify mechanism for calorie restriction to reduce inflammation

    Yale School of Medicine researchers found that moderate calorie restriction reduces age-related inflammation by lowering levels of the pro-inflammatory protein fragment C3a.

  2. [HEALTH] 2 sources
    Caloric restriction and diet linked to reduced chronic inflammation

    Research indicates that moderate caloric restriction and specific dietary choices can reduce C3a protein levels and chronic inflammation, potentially supporting healthier aging.

Sources

dobrewiadomosci.net.pl · farmacoecura.it · medonet.pl · microbiologiaitalia.it · tech.wp.pl