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Genetic study of Jonathan the tortoise

Overview

Researchers have conducted a genetic study on Jonathan, a 194-year-old Aldabra giant tortoise, to understand the biological mechanisms behind his extreme longevity. Published in the journal ‘Science Advances’, the research analyzed his genome and epigenome to determine how he has exceeded the typical species lifespan of approximately 90 years.

The study identified 287 unique genetic variants that appear to protect against cellular damage, specifically involving DNA repair and telomere function. Scientists observed that Jonathan maintains stable mitochondrial function and gene activity that typically degrades with age in other animals and humans. Co-author Justin Gerlach from the University of Cambridge noted that the tortoise’s slower metabolism may result in fewer chemical reactions and less cellular and DNA damage.

Recent analysis further specifies that these 287 variants are associated with reduced inflammatory processes. While the findings provide a biological roadmap for studying longevity, researchers emphasized that additional study is necessary to determine if these specific mechanisms could eventually be applied to human anti-aging therapies. Jonathan currently resides on the island of Saint Helena in the South Atlantic.

Entities

Jonathan · University of Cambridge · Science Advances · Aldabra giant tortoise · Saint Helena

Timeline

  1. [TECHNOLOGY] 5 sources
    Jonathan the giant tortoise's DNA reveals longevity secrets

    Genetic analysis of Jonathan, a 194-year-old giant tortoise, has revealed 287 gene variants linked to DNA repair and cellular protection, offering potential clues for human longevity research.

  2. [TECHNOLOGY] 27 sources
    Jonathan the 194-year-old tortoise reveals genetic secrets of longevity

    Scientists studying the 194-year-old tortoise Jonathan have identified unique genetic variants and epigenetic patterns that may explain his extraordinary longevity and resistance to cellular aging.

Sources

20minutos.com.mx · aeiou.pt · amica.de · bbv-net.de · bl-portal.com · caminodesantiago.lavozdegalicia.com · cnn.gr · courage-online.de · devdiscourse.com · focusjunior.it · gbnews.com · hna.de · mayacomunicacion.com.mx · naftemporiki.gr · nczas.info · ndmais.com.br · newsfeed.zeit.de · nordbayern.de · op-online.de · radiokollasuyo.bo · saarbruecker-zeitung.de · scientificamerican.com · sputnikportal.rs · stimberg-zeitung.de · studyfinds.org · telegraf.rs · theguardian.com · ultimahora.com · vesti.bg · volksfreund.de · zielona.interia.pl · zmescience.com

This summary has been updated 1 time: see revision history