< Back to situations

Monitor this situation.

[SITUATION] · [ACTIVE] · [HEALTH]

2 clusters · 5 sources · 5 days · First seen · Last updated

Impact of sweeteners on intergenerational metabolic health

Overview

Research published in ‘Frontiers in Nutrition’ by the Universidad de Chile suggests that the non-nutritive sweeteners sucralose and stevia may cause biological changes that persist across generations.

Using mouse models, researchers found that consuming these sweeteners can alter gut microbiome composition, reduce the production of beneficial substances like short-chain fatty acids, and influence gene activity related to metabolism, inflammation, and intestinal barrier function.

A key finding of the study is that these physiological changes, including impacts on glucose tolerance, were observed in subsequent generations of mice even when those offspring were given only plain water and never consumed the sweeteners themselves. While researchers noted this does not prove sweeteners are the cause of rising obesity or insulin resistance trends, the findings raise questions regarding how these additives influence metabolism across generations.

Entities

Universidad de Chile · Francisca Concha Celume · Frontiers in Nutrition

Timeline

  1. 7 days ago

    [HEALTH] 2 sources
    Universidad de Chile study links sweeteners to intergenerational health changes

    A study by Universidad de Chile suggests that sucralose and stevia can alter gut microbiomes and metabolic gene activity in ways that persist in subsequent generations, even without direct exposure.

  2. 11 days ago

    [HEALTH] 3 sources
    Sweeteners sucralose and stevia may impact metabolic health across generations

    A study published in Frontiers in Nutrition suggests that sucralose and stevia may alter gut microbiomes and gene activity in mice, with some effects persisting in subsequent generations.

Sources

angel-wings.nl · medonet.pl · naukawpolsce.pap.pl · sciencedaily.com · senseaboutscience.org.uk