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2 clusters · 229 sources · 2 days · First seen 1 day ago · Last updated about 4 hours ago

Moderna and Merck melanoma vaccine clinical trials

Overview

Moderna and Merck reported positive interim results from a Phase 3 clinical trial for Intismeran autogene, an experimental personalized mRNA cancer vaccine. The therapy, administered alongside Merck’s immunotherapy Keytruda, was tested on 1,137 patients with high-risk or advanced melanoma.

The INTerpath-001 study met its primary endpoint by demonstrating a statistically significant improvement in recurrence-free survival compared to Keytruda alone, and met a secondary endpoint by reducing the risk of distant metastasis. Following the announcement of the trial success, Moderna’s stock experienced a significant increase.

Entities

Moderna · Intismeran autogene · Melanoma Institute Australia · Merck · Georgina Long

Timeline

about 4 hours ago

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1 day ago

[HEALTH] 228 sources FAST-MOVING
Moderna and Merck report positive Phase 3 results for personalized mRNA melanoma vaccine
Moderna and Merck reported positive Phase 3 trial results for Intismeran, a personalized mRNA cancer vaccine that significantly improved recurrence-free survival in high-risk melanoma patients when paired with

Sources

13tv.es · 20minutos.es · 324.cat · 6yka.com · abcnews.al · abendblatt.de · ad-hoc-news.de · agenparl.eu · aimatmelanoma.org · aktivni.si · aljazeera.com · altonivel.com.mx · americafirstreport.com · americanindependent.com · anlatilaninotesi.com.tr · anleihencheck.de · antiguatribune.com · apjii.or.id · arabic.euronews.com · arabnews.pk · aripaev.ee · arstechnica.com · arynews.tv · athina984.gr · augsburger-allgemeine.de · baocalitoday.com · barbadosgazette.com · beteve.cat · bigodino.it · biomedicalcue.it · bitcoinethereumnews.com · biznis.rs · block-builders.de · blocktempo.com · bors-nliv.svd.se · brasilemfolhas.com.br · bs-media.de · bydlet.cz · cafebiz.vn · cafef.vn · capital.gr · cash.ch · cbsnews.com · communitynews.com.au · contrapunto.com · correiodecarajas.com.br · cryptoast.fr · CT24.cz