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2 clusters · 6 sources · 7 days · First seen about 1 month ago · Last updated 29 days ago

NeOnc Technologies NEO100 clinical trial progress

Overview

NeOnc Technologies Holdings announced plans to present topline results from the Phase 2a portion of its NEO100-01 clinical trial, which evaluates the safety and efficacy of intranasal NEO100 in patients with recurrent or progressive Grade III and Grade IV IDH1-mutant glioma.

Following the announcement, the company reported positive Phase 2a data, noting a 48.9% six-month progression-free survival rate, which exceeded the prespecified historical benchmark of 20%. The reported median overall survival was 26.09 months.

NEO100 utilizes a non-invasive nose-to-brain delivery method intended to overcome the blood-brain barrier. The drug holds FDA Orphan Drug, Fast Track, and Rare Pediatric Disease designations. NeOnc intends to request a Type B FDA meeting to discuss a registrational development path and has received UAE IND authorization for its NEO100 programs.

Entities

Nasdaq · NeOnc Technologies Holdings · University of Southern California · Karyopharm Therapeutics Inc. · FDA

Timeline

29 days ago

[BUSINESS] 3 sources
NeOnc Technologies reports positive Phase 2a data for NEO100
NeOnc Technologies reported Phase 2a results for NEO100, showing a 48.9% six-month progression-free survival rate in treating recurrent high-grade glioma via nose-to-brain delivery.
about 1 month ago

[BUSINESS] 3 sources
Karyopharm and NeOnc announce upcoming financial and clinical updates
Karyopharm Therapeutics will report Q2 2026 financial results on August 13, while NeOnc Technologies plans to present Phase 2a clinical trial data for its glioma therapy on August 12.

Sources

aijourn.com · crypto-reporter.com · iliveupstairs.com · last10k.com · memesita.com · stocktitan.net