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Obesity and its link to cardiometabolic disease risk

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2026-08-19 05:29 UTC → 2026-08-23 08:15 UTC · added ~~removed~~

Research continues to establish obesity as a chronic, multifactorial disease that drives a spectrum of cardiometabolic conditions. A study of Brazilian adults detailed how obesity‑related visceral fat drives age‑dependent rises in hypertension, dyslipidaemia, and insulin resistance. Dr. Júlia Chagas noted that excess visceral fat is not merely an energy depot but is “metabolically active and produces inflammatory substances that interfere with insulin action in cells,” potentially leading to type 2 diabetes and neurodegenerative disorders. On a global scale, the World Health Organization reported that over a billion people were living with obesity in 2022. Medical experts emphasize that visceral fat promotes inflammation and atherosclerosis, increasing the risk of coronary artery disease, heart failure, and stroke. Recent findings from Sweden and the UK have further quantified these risks. A SWEDEHEART analysis of over 124,000 patients in Sweden found that individuals with both class 3 obesity (BMI ≥40 kg/m²) and diabetes faced more than twice the risk of all-cause mortality and a 91% higher risk of major adverse cardiovascular events following a myocardial infarction compared to those with a normal BMI and no diabetes. Severe obesity was specifically linked to increased rates of heart failure and kidney complications. In Turkey, medical experts have reinforced these links, noting that obesity acts as a primary driver of metabolic diseases that can lead to coronary artery disease and severe heart failure. To mitigate these risks, specialists recommend a combination of healthy diet, regular physical activity, adequate sleep, and smoking cessation. Additionally, research involving UK Biobank data suggests that adhering to a Mediterranean lifestyle—incorporating specific dietary patterns, regular physical activity, and adequate sleep—is associated with a reduced risk of cardiovascular mortality among adults with type 2 diabetes.

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