Prolonged melatonin use linked to 89% higher heart failure risk

A study presented at the American Heart Association scientific meeting indicates that long-term melatonin use is associated with an 89% increased risk of developing heart failure. The research analyzed records from 130,828 adults diagnosed with insomnia, divided into two equal groups of 65,414 participants.

Among the group that used melatonin for at least one year, researchers identified 3,021 cases of heart failure over a five-year follow-up period, compared to 1,797 cases in the group that did not use the supplement. The analysis also noted higher rates of heart failure-related hospitalizations and deaths from various causes among melatonin users.

Researchers emphasized that these findings represent a statistical association observed in records and that other factors may influence the results. They stressed the need for further direct research to investigate the cardiovascular safety of melatonin, particularly during prolonged use.