Big 12 college football matchups

The Big 12 Conference enters its second week of the season with several high-profile matchups. A primary game features No. 15 BYU hosting Arizona in Provo. Both teams entered the week undefeated after dominant opening performances: BYU secured a 63-7 victory over Utah Tech, while Arizona defeated Northern Arizona 35-7. The matchup revives a historic rivalry, with Arizona seeking revenge for a double-overtime loss to the Cougars last season.

In the CyHawk Series, Iowa State travels to face No. 21 Iowa. Iowa enters the contest following a 40-0 shutout of Northern Illinois, while Iowa State is coming off a 38-10 win against Southeast Missouri State. Despite Iowa being favored, recent history suggests a close contest, as the last four meetings between the rivals were decided by a combined 14 points.

The matchup marks a significant transition for the Cyclones, who are entering the rivalry under first-year head coach Jimmy Rogers following the departure of Matt Campbell to Penn State. Iowa enters the contest as a heavy betting favorite, with lines ranging between 13.5 and 14.5 points. While Iowa leads the all-time series 46-25 or 47-25 depending on the source, Iowa State has won the last two meetings in Iowa City.