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2 clusters · 6 sources · 2 days · First seen 18 days ago · Last updated 16 days ago

Genetic influence on low-carb diet cholesterol response

Overview

Research presented at the American Society for Nutrition's NUTRITION 2026 meeting suggests that genetic makeup influences how individuals respond to low-carbohydrate diets regarding LDL cholesterol levels. Using data from the DIETFITS randomized controlled trial, researchers investigated why dietary responses vary significantly between people.

The findings indicate that saturated fat, a common component of low-carb diets, may interact with a person's genetic background to drive higher cholesterol levels. While some individuals see little to no change, others may experience a sharp rise in LDL cholesterol, potentially increasing the risk of heart disease, heart attack, and stroke.

Lead author Alexa Barad, PhD, RDN, noted that dietary advice is not “one-size fits all,” highlighting that genetic sensitivity to saturated fat plays a critical role in determining how these dietary patterns affect heart disease risk factors.

Entities

Alexa Barad · Stanford University School of Medicine · American Society for Nutrition

Timeline

16 days ago

[HEALTH] 2 sources
Stanford research links low-carb diets to rising cholesterol risks
Stanford University researchers warn that low-carb diets may cause a dangerous rise in LDL cholesterol for some individuals, potentially increasing the risk of heart disease and stroke.
18 days ago

[HEALTH] 4 sources
Genetics may influence LDL cholesterol response to low-carb diets
New research suggests genetics may determine if a low-carb diet raises LDL cholesterol, as some individuals appear more sensitive to the effects of saturated fat due to their genetic background.

Sources

bestoflifemag.com · dailymail.co.uk · insideprecisionmedicine.com · sciencedaily.com · senseaboutscience.org.uk · teatronaturale.it