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8 clusters · 38 sources · 77 days · First seen · Last updated

Shingles trends and Shingrix vaccine research

Overview

Recent data indicates a significant rise in shingles cases among younger adults, particularly millennial women in the United States and the United Kingdom. Research shows that cases among adults aged 30–49 in the U.S. more than doubled between 1998 and 2017, with activity in the U.K. currently exceeding the five-year average. Following the recommendation of the Shingrix vaccine to combat these rising rates, new research suggests the vaccine may offer additional health benefits. An analysis from the University of Oxford indicates that Shingrix is associated with a 9% lower overall cardiovascular disease burden, including a 10% reduction in ischemic heart disease risk and a 12% reduction in heart failure risk. Further findings published in Nature Medicine and the Annals of Internal Medicine noted a 12% lower stroke risk in men. Newer analysis of health records for adults aged 60 and older over a seven-year period suggests the vaccine is also associated with a 7% lower burden of atrial fibrillation. A study published in Nature Medicine, analyzing data from over 70,000 U.S. adults aged 60 and older, tracked the transition from the older Zostavax vaccine to Shingrix starting in October 2017. This research corroborated that Shingrix recipients experienced a 10% reduction in coronary heart disease risk and a 12% reduction in heart failure risk for both men and women. Additionally, a large-scale study from Brown University involving over 500,000 individuals found that Shingrix was associated with a 24% lower risk of dementia among adults aged 66 and older. This potential link was further supported by a natural experiment in Wales, where vaccinated individuals had approximately a 20% lower chance of developing dementia. Driven by these findings, demand for the shingles vaccine is increasing significantly across British pharmacies, with major chains reporting substantial rises in bookings.

Entities

Shingrix · University of Oxford · Zostavax · Brown University · Nature Medicine

Claims

What the coverage asserts, and how many sources carry each claim.

Coverage disagrees

Sources make claims that cannot both be true. CLSTR reports the disagreement; it does not decide who is right.

  • "Men receiving the Shingrix vaccine showed a 12% lower risk of stroke compared to those receiving Zostavax."

    vs

    "The recombinant shingles vaccine is linked to a 12 percent reduction in stroke risk."

    One claim asserts a 12% lower risk of stroke for men, while the other asserts a 12% reduction in stroke risk generally, but they are distinct enough in scope that they do not strictly contradict; a 12

  • "The recombinant Shingrix vaccine is associated with a 9% reduction in cardiovascular disease burden over seven years compared to the Zostavax vaccine."

    vs

    "Shingrix recipients had a 12 percent lower risk of cardiovascular diagnosis over 3.5 years."

    One claim asserts a 9% reduction in cardiovascular disease burden over seven years, while the other asserts a 12% lower risk of cardiovascular diagnosis over 3.5 years.

Timeline

  1. [HEALTH] 2 sources
    Shingles vaccine demand rises amid potential dementia prevention links

    Rising demand for the shingles vaccine is being driven by research suggesting a potential link between vaccination and a reduced risk of dementia, particularly in women.

  2. [HEALTH] 2 sources
    Medical research links shingles vaccines to lower dementia risk and identifies new neuralgia drivers

    Research indicates that exosomes may drive postherpetic neuralgia, while the Shingrix shingles vaccine is linked to a 24% reduction in dementia risk.

  3. [HEALTH] 5 sources
    Shingrix vaccine may reduce dementia and heart disease risks

    A University of Oxford study published in Nature Medicine suggests the Shingrix shingles vaccine may reduce risks of dementia and heart disease by up to 12 percent.

  4. [HEALTH] 6 sources
    Shingles vaccine linked to lower risks of heart disease and dementia

    Studies suggest the Shingrix shingles vaccine may reduce the risk of cardiovascular diseases, including stroke and heart failure, and may also lower the risk of dementia in older adults.

  5. [HEALTH] 4 sources
    Shingrix vaccine linked to lower cardiovascular disease risk

    A study published in Nature Medicine suggests the Shingrix shingles vaccine is linked to a lower risk of heart attack, stroke, and heart failure in adults aged 60 and older.

  6. [HEALTH] 4 sources
    Shingles vaccine linked to lower dementia risk in Welsh study

    A shingles vaccine used in a Welsh national program may reduce dementia risk by 20%, according to researchers studying a natural age-based eligibility experiment.

  7. [HEALTH] 16 sources
    Shingrix vaccine linked to lower dementia and cardiovascular risks

    Studies link the recombinant shingles vaccine, Shingrix, to a 9% reduction in cardiovascular disease burden and a 24% lower risk of dementia in older adults compared to previous vaccine versions.

  8. [HEALTH] 2 sources
    Shingles Cases Surge in Young Adults, Shingrix Vaccine Recommended

    Shingles cases have risen sharply among adults 30‑49, especially millennial women in the US and UK, prompting health officials to stress the highly effective Shingrix vaccine for protection.

Sources

ad-hoc-news.de · astig.ph · bild.de · borncity.com · descopera.ro · digitalcommons.library.tmc.edu · diken.com.tr · en.etemaaddaily.com · fractal.org.za · gbnews.com · haberkaos.com · hna.de · hnonline.sk · ilfogliettone.it · independent.co.uk · insideprecisionmedicine.com · it-boltwise.de · kreiszeitung.de · kurierverlag.de · leinetal24.de · livenowfox.com · mediafax.ro · medicaldaily.com · medicaldialogues.in · multiplesclerosisnewstoday.com · news-medical.net · novinky.cz · oxfordhealthbrc.nihr.ac.uk · radiokollasuyo.bo · rocketnews.com · statnews.com · t-online.de · theguardian.com · thelifesciencesmagazine.com · timesng.com · tz.de · wochentlich.de · zurnal.pravda.sk

This summary has been updated 8 times: see revision history